In 2013, the Ugandan government secured a loan from AfDB and NTF. The purpose was to rehabilitate and improve Mulago National Referral Hospital, construct Kawempe Referral Hospital and Kiruddu Referral Hospital to reorganize healthcare delivery in Kampala. Kiruddu Referral Hospital would shift the patient burden from Mulago National Referral Hospital as part of the new envisaged national referral system.

Kiruddu Referral Hospital is in the neighborhood of Kiruddu, on Buziga Hill, in Makindye Division, one of the five administrative units of the Kampala Capital City Authority. The hospital opened to the public on 16 May 2016. Kiruddu has two main specialties including Internal Medicine, burns and plastic surgery. As at August 2016, Kiruddu Hospital’s fourteen specialized outpatient clinics serve about 250 patients daily.The Hospital also has other mandates besides clinical care and these include; training students from medical teaching universities and provides an enabling environment for carrying out research.